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Index > Protein center > SLC22A18(Gene name) > Human
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  • SLC22A18 (Gene name),
  • Solute carrier family 22 member 18 (Protein name ),  S22AI_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC22A18(BWR1A;BWSCR1A;HET;IMPT1;ITM;ORCTL2;SLC22A1L;TSSC5);
    Protein name:
    Solute carrier family 22 member 18;
    Alternative:
    Efflux transporter-like protein;Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein;Organic cation transporter-like protein 2(ORCTL-2);Imprinted multi-membrane-spanning polyspecific transporter-related protein 1;Tumor-suppressing STF cDNA 5 protein;Solute carrier family 22 member 1-like;p45-Beckwith-Wiedemann region 1 A(p45-BWR1A);Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with RNF167.
    Function:
    May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney.
    Subcellular Location:
    Apical cell membrane Multi-pass membrane protein Localized at the apical membrane surface of renal proximal tubules.
    Protein Attributes:
    Sequence length:
    424
    Sequence:
    50:
    MQGARAPRDQ | GRSPGRMSAL | GRSSVILLTY | VLAATELTCL | FMQFSIVPYL | 
    100:
    SRKLGLDSIA | FGYLQTTFGV | LQLLGGPVFG | RFADQRGARA | ALTLSFLAAL | 
    150:
    ALYLLLAAAS | SPALPGVYLL | FASRLPGALM | HTLPAAQMVI | TDLSAPEERP | 
    200:
    AALGRLGLCF | GVGVILGSLL | GGTLVSAYGI | QCPAILAALA | TLLGAVLSFT | 
    250:
    CIPASTKGAK | TDAQAPLPGG | PRASVFDLKA | IASLLRLPDV | PRIFLVKVAS | 
    300:
    NCPTGLFMVM | FSIISMDFFQ | LEAAQAGYLM | SFFGLLQMVT | QGLVIGQLSS | 
    350:
    HFSEEVLLRA | SVLVFIVVGL | AMAWMSSVFH | FCLLVPGLVF | SLCTLNVVTD | 
    400:
    SMLIKAVSTS | DTGTMLGLCA | SVQPLLRTLG | PTVGGLLYRS | FGVPVFGHVQ | 
    424:
    VAINTLVLLV | LWRKPMPQRK | DKVR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    KEGG:
    MIM:
    Pfam:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Solute carrier family 22 member 18
    Cat.:
    E11021m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Solute carrier family 22 member 18
    Cat.:
    E11021h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Solute carrier family 22 member 18
    Cat.:
    E11021r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Solute carrier family 22 member 18
    Cat.:
    U11021m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Solute carrier family 22 member 18
    Cat.:
    U11021h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Solute carrier family 22 member 18
    Cat.:
    U11021r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Solute carrier family 22 member 18
    Cat.:
    P11021Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Solute carrier family 22 member 18
    Cat.:
    P11021Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Solute carrier family 22 member 18
    Cat.:
    P11021Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Solute carrier family 22 member 18
    Monoclonal Antibody for Human Solute carrier family 22 member 18
    Monoclonal Antibody for Human Solute carrier family 22 member 18
    Protein for Human Solute carrier family 22 member 18
    Protein for Human Solute carrier family 22 member 18
    Protein for Human Solute carrier family 22 member 18

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    Precision
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    Linearity
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    References
    1. 1.
      "Somatic mutation of TSSC5, a novel imprinted gene from human chromosome 11p15.5."
      Lee M.P. , Reeves C. , Schmitt A. , Su K. , Connors T.D. , Hu R.J. , Brandenburg S. , Lee M.J. , Miller G. , Feinberg A.P.
      Cancer Res.58:4155-4159(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLN-309;VARIANT LUNG CANCER PHE-233
    2. 2.
      "A novel gene, ITM, located between p57KIP2 and IPL, is imprinted in mice."
      Morisaki H. , Hatada I. , Morisaki T. , Mukai T.
      DNA Res.5:235-240(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain."
      Cooper P.R. , Smilinich N.J. , Day C.D. , Nowak N.J. , Reid L.H. , Pearsall R.S. , Reece M. , Prawitt D. , Landers J. , Housman D.E. , Winterpacht A. , Zabel B.U. , Pelletier J. , Weissman B.E. , Shows T.B. , Higgins M.J.
      Genomics49:38-51(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;VARIANT GLN-12
    4. 4.
      "IMPT1, an imprinted gene similar to polyspecific transporter and multi-drug resistance genes."
      Dao D. , Frank D. , Qian N. , O'Keefe D. , Vosatka R.J. , Walsh C.P. , Tycko B.
      Hum. Mol. Genet.7:597-608(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Placenta.
    5. 5.
      "Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples."
      Schwienbacher C. , Sabbioni S. , Campi M. , Veronese A. , Bernardi G. , Menegatti A. , Hatada I. , Mukai T. , Ohashi H. , Barbanti-Brodano G. , Croce C.M. , Negrini M.
      Proc. Natl. Acad. Sci. U.S.A.95:3873-3878(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS THR-6 AND GLN-12; CYS-86;TISSUE SPECIFICITY
    6. 6.
      "Monoallelic expression of the gene encoding a human efflux transporter like protein (HET), on chromosome 11p15.5."
      Chen P. , Shen W. , Karnik P.
      Submitted (1998-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLN-12
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLN-12
      tissue: Placenta.
    8. 8.
      "Functional characterization of ORCTL2 -- an organic cation transporter expressed in the renal proximal tubules."
      Reece M. , Prawitt D. , Landers J. , Kast C. , Gros P. , Housman D. , Zabel B.U. , Pelletier J.
      FEBS Lett.433:245-250(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    9. 9.
      "Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105."
      Yamada H.Y. , Gorbsky G.J.
      Oncogene25:1330-1339(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF167
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